<p>Startup Colossal has announced de-extinction — three "puppies" of the dire wolf have been born: Romulus, Remus, and Khaleesi. This is the result of large-scale DNA editing using CRISPR — scientists took ancient samples (up to 72,000 years old) and integrated genome fragments into the cells of a gray wolf.</p>
<p>The result is not the original species, but a hybrid: a functional analogue created from a modern wolf with parts of the dire wolf's DNA. This approach has sparked controversy. Critics remind us that dire wolves are not just large wolves, but a separate evolutionary line incompatible with modern surrogates. Even with perfect DNA, it wouldn’t be a "resynthesis of the species." </p>
<p>Nevertheless, the achievement is significant: over 20 point mutations in 14 genes, restoring traits — from fur to body size. Colossal calls this a "functionally equivalent species" — a biological reconstruction without claiming full identity.</p>
<p>The main question now is not about science, but about intentions. Is this Jurassic Park or a step towards saving endangered species?</p>
📝 Source: https://colossal.com/direwolf
